- Comorbid conditions (eg serious cardiac illness, renal insufficiency, poor general conditions)
- Concomitant use of heparin
- INR level
- Worsening liver dysfunction
Controlling these independent risk factors will reduce their associated risk of bleeding
Number of comorbid condns at start of therapy | One (+1) Two (+2) Three (+3) |
Concomitant use of heparin | Age 60-79 yrs (+2) Age 80 or more (+4) |
INR level | 2.0 - 2.9 (+1) 3.0 or more (+2) |
Worsening liver dysfunction during therapy (bilirubin rising to 4 mg/dl (68.4 umol/L) or more) | Yes (+2) |
- low risk: 0 - 2 points
- moderate risk: 3 - 4 points
- high risk: 5 or more points
.Anticoagulation
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